Cardiff Blues boss David Young believes his team must "throw caution to the wind" when they tackle Heineken Cup heavyweights Toulouse tomorrow.
The Blues face a daunting task in their bid to reach this season's semi-finals.
And while Young accepts the degree of difficulty is a considerable one, he does not want his players wondering what might have been.
Young said: "It will be a massive hurdle for us - we are certainly going up in standard of who we are playing against.
"Toulouse haven't got their standing in the Heineken Cup by chance - they've earned it.
"They are always in the top four or five in Europe, and they have a galaxy of world stars. We know that on any given day they can put teams to the sword.
"We are very respectful of what they can do, but we are concentrating on ourselves.
"We've got to go out there and not sit back and not try to lose the game. We've got to go out there and try to win it by taking the game to them.
"We've got to go over there and throw caution to the wind and try to express ourselves. We need a little bit of luck, as every team does, but it's a challenge we are running towards, not away from."
Toulouse, who include France scrum-half Jean-Baptiste Elissalde at number 10, will start as firm favourites in their quest for a fourth European title.
But they will also have concerns for coach Guy Noves, who was taken to hospital by helicopter yesterday after his bicycle collided with a car in Toulouse city centre.
The 54-year-old was initially knocked out, and while he has undergone further examination, his injuries are not thought to be life-threatening.
Alan Gaffney hopes his Saracens side can give the Ospreys food for thought in tomorrow's quarter-final showdown at Vicarage Road.
A fortnight after Saracens were smashed 30-3 by Shane Williams and company in the EDF Energy Cup, both sides' European ambitions now go on the line.
Neither team has previously progressed beyond the Heineken Cup last-eight, but despite having home advantage, Saracens will start as underdogs.
They have drifted away from the Guinness Premiership play-off pace during recent weeks, while their opponents this weekend are still chasing silverware on domestic and European fronts.
Gaffney said: "We didn't do ourselves justice against the Ospreys two weeks ago, and we want to put that right.
"There is no doubt we are the underdogs for the game, but the determination is to go out there and put on a performance.
"We have to give the Ospreys their due, because two weeks ago they took their chances well and were the better team.
"We were on the back foot from the opening minutes, and it stayed that way for the majority of the game.
"But we are going into the game confident we will play a lot better than two weeks ago - we have to.
"We also have to play a lot cuter. The Ospreys are a side who have grown together over a number of years and are very professional in how they play in all areas of the pitch."
Gaffney has recalled international trio Andy Farrell, Cobus Visagie and Richard Hill, but the Ospreys have been dealt a second injury blow.
Scotland wing Nikki Walker is expected to be sidelined for a month after suffering a stress fracture of his right fibia.
He joins Wales scrum-half Mike Phillips, who is nursing a serious knee injury, in missing the Ospreys' trip to Watford.
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