Veteran flanker George Smith will return to the Australia pack for Saturday's international against England at Twickenham after missing last week's match against the New Zealand All Blacks.

Smith, who is fifth on the all-time list of capped players, replaces David Pocock for what will be his 107th cap.

"We were looking to give George this one," Australia's assistant coach Jim Williams told reporters. "Poe played outstandingly in Tokyo but we monitor wellbeing week to week.

The Wallabies have also re-jigged their midfield with Digby Ioane and Quade Cooper paired at centre.

Ioana, 24, who returned from a shoulder injury to play against the All Blacks on the wing, will switch to centre alongside state colleague Cooper. The two Queensland Reds players have just 12 caps between them.

"Tuesday (against Gloucester) was influential for us in terms of Quade's selection. He just showed how he is coming of age and he has been rewarded for that," said Smith.

Ioane's shift means Drew Mitchell, scorer of two tries against Gloucester on Tuesday, returns to the wing after he missed out on the Tokyo match.

Only eight of the Australia side who beat England 28-14 last year will feature on Saturday against an England team with just four survivors.

"We do have a group that's not that experienced in terms of test caps -- it's not as if we've left a lot at home who could play. This is our best group and England's best group," said Walabies coach Robbie Deans.

"It's going to be a ferocious contest. It's England at Twickenham, that's the way it is, we will have to work for everything we get."

(Editing by John Mehaffey)