LONDON (Reuters) - Modest Barnsley will look to cause another FA Cup shock when they meet holders Chelsea in the quarter-finals on Saturday (5:30 p.m.).

The mid-table Championship (second division) side stunned Liverpool with a late winner at Anfield in the last round and their reward is a home tie against Avram Grant's team.

It is only the second time Chelsea and Barnsley have met in the Cup, the Londoners losing their only previous clash 4-0 in 1988-89.

Chelsea were 6-0 winners on their last visit to Oakwell in the Premier League in 1997.

Midfielder Frank Lampard is available after escaping a three-match ban when the Football Association upheld an appeal against his red card in Saturday's 4-0 win at West Ham United.

Lampard was sent off for violent conduct after a seemingly innocuous exchange of shoves with West Ham's Luis Boa Morte.

Last year's beaten finalists Manchester United, bidding to reach a fourth semi-final in five years, host Portsmouth on Saturday (12:45 p.m.).

United, who have only faced Premier League opposition in this season's competition, and Portsmouth met in the fourth round last year when two outstanding goals from Wayne Rooney gave the home side a narrow 2-1 victory at Old Trafford.

"It'll be tough," United midfielder Michael Carrick told the club's Web site (www.manutd.com). "They've been in good form away from home this season.

"They've got a lot of pace and attacking threat but if we are on our game then we should win."

Championship club Cardiff City, in the last eight for the first time since winning the FA Cup in 1927, travel to Premier League Middlesbrough on Sunday (2 p.m.).

A team from outside the top-flight is guaranteed a semi-final place with League One (third division) Bristol Rovers, the lowest-ranked team left in the competition, entertaining Championship outfit West Bromwich Albion on Sunday (6 p.m.).

Rovers, in the quarter-finals for the first time since 1958, dumped out Premier League Fulham in a third-round replay and accounted for Southampton in the last round.

Millwall, in 2004, were the last club from outside the top-flight to reach the final.

(Editing by Tony Jimenez and Alastair Himmer)