Danny Fox and Billy Sharp return to the Southampton squad for the visit of Burnley.
Former Clarets full-back Fox missed Tuesday's 3-2 FA Cup replay defeat by Millwall through suspension and striker Sharp was ineligible.
Sharp could be handed his full debut in attack having made one substitute appearance since his January switch from Doncaster.
Defender Jos Hooiveld is set to miss out again with a hamstring problem but boss Nigel Adkins has an otherwise fully-fit squad.
Goalkeeper Kelvin Davis and midfielders Jack Cork and Morgan Schneiderlin were rested in midweek and return along with top scorer Rickie Lambert, who came on as a substitute.
Tottenham loanee Iago Falque could also be added to the squad after he was cup-tied.


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