Australian Open - Wildcards confirmed for Melbourne
The 16-year-old Keys overcame Gail Brodsky 6-3 6-4 on Sunday to earn a women's wildcard, while Levine battled past veteran Robby Ginepri 6-0 6-2 6-1 to seal a men's spot.
Two American and two French players are guaranteed wildcard berths in the Australian Open every year as a result of a reciprocal agreement between the US, French and Australian tennis associations.
Under the agreement, Casey Dellacqua and Marinko Matosevic received wildcards into the 2011 US Open.
The 15-year-old Ashleigh Barty and Matosevic both won wildcard playoffs in Australia this month to secure spots in the tournament, which begins on January 16.
Two-time grand slam winner Lleyton Hewitt, Dellacqua and Matthew Ebden have also received wildcards.