The last time Tottenham beat Arsenal in the league, Pitt the Younger was Prime Minister and the average London house price was three guineas.

Read on for team news or click the links on the right for predicted line-ups.

Arsenal v Tottenham Hotspur (12.45pm)

Arsenal's injury woes are a thing of the past with Theo Walcott their only real doubt. Robin van Persie should start up alongside Emmanuel Adebayor in front of a full strength Hleb-Fabregas-Flamini-Rosicky midfield. Spurs have Robbie Keane back from suspension but Didier Zokora is banned. Ledley King is no more than a long shot after a long spell out injured.

Aston Villa v Manchester City

Martin O'Neill rarely springs a selection surprise, with six players ever-present and Zat Knight having somehow played 18 games in 17 match days for Fulham and Villa. Joe Hart will play in goal for City after Sven-Goran Eriksson made him his number one, while Elano returns to his attacking midfield role. Midfielder Michael Johnson is doubtful and Stephen Ireland is suspended.

Bolton Wanderers v Birmingham City

Andy O'Brien has come back from food poisoning and will play in central defence, while Kevin Nolan has overcome a foot complaint. Heidar Helguson could make the bench after injury. Birmingham are without suspended defender Liam Ridgewell but Damien Johnson is back in contention. Mehdi Nafti also returns, but Stuart Parnaby has a foot injury and is absent.

Fulham v Wigan Athletic

Ray Lewington and Billy McKinlay lead managerless Fulham into this relegation six-pointer but are unlikely to make sweeping changes at such short notice. Jimmy Bullard is still frustratingly shy of fitness despite playing for the reserves in midweek. Emile Heskey could start after making a swift recovery from his ankle injury.

Liverpool v Portsmouth

Rafa's merry-go-round continues, but Fernando Torres is a certain starter after being rested for Wednesday's game against Chelsea. Peter Crouch was sent off in that game and is suspended. Xabi Alonso is fit, Steve Finnan doubtful and Daniel Agger out. Pompey have no Noe Pamarot and Hermann Hreidarsson, back from suspension, should deputise.

Middlesbrough v West Ham United

Boro have Fabio Rochemback suspended and Julio Arca - the preferred choice to replace him in central midfield - is rated as 50-50. Otherwise Lee Cattermole could come in. West Ham have 11 players on their injury list. Freddie Ljungberg is expected to miss out because of a migraine, while James Collins is very doubtful. Luis Boa Morte could return.

Reading v Sunderland

Brynjar Gunnarsson is Steve Coppell's main concern, with a knee injury, and Kalifa Cisse is standing by. John Oster and Glen Little remain on the sidelines. Sunderland are without Irish midfielder Liam Miller, who is suspended. Kieran Richardson could make his return from a back injury as a substitute, but Nyron Nosworthy and Russell Anderson are unlikely to play.

Manchester United v Everton (12pm Sunday)

No new injuries for the champions, who were the only side of the big four not to play in midweek. Gary Neville is very close to returning from injury but may not start. Everton played a surprisingly strong side for their meaningless UEFA Cup game in Alkmaar on Thursday but managed to avoid any new injuries. Leon Osman, Leighton Baines and Alan Stubbs are all out.

Newcastle United v Derby County (2pm Sunday)

Steven Taylor's hamstring trouble has eased but the England Under-21 may not be able to force his way back into the side. Michael Owen is not ready to return yet. Derby have four players - Stephen Pearson, Andy Griffin, Marc Edworthy and Robert Earnshaw - doubtful. The former two are both expected to start at St James's.

Blackburn Rovers v Chelsea (4.10pm Sunday)

Brett Emerton plays for Blackburn, having served a suspension in midweek, as does Ryan Nelsen but Chris Samba is now banned. Matt Derbyshire could replace the out-of-form Benni McCarthy. Chelsea are without John Terry. Alex is in the squad after returning from Brazil but Avram Grant should go with Tal Ben Haim.

Alex Chick / Eurosport