Hilario is set to start in the Chelsea goal after number one Petr Cech picked up a hip injury in Sunday's win over Blackburn.

Chelsea v Aston Villa (13.00)

Goalkeeper Hilario looks set to fill in for Petr Cech, who is a serious doubt for Chelsea after picking up a hib injury against Blackburn, adding to the growing injury list for Avram Grant, with skipper John Terry and star striker Didier Drogba both already out. Martin O'Neill has no new injury worries as his side bid to repeat their shock victory from earlier this season.

West Ham v Reading (13.00)

Hammers boss Alan Curbishley has no new injury worries following the last-gasp win over Middlesbrough. Reading midfielder Brynjar Gunnarsson will miss the festive period after picking up a knee injury in the draw against Fulham, summer signing Kalifa Cisse is set to replace him.

Tottenham v Fulham (13.00)

Juande Ramos is likely to stick with young midfielder Jamie O"Hara after impressing in the defeat against Arsenal, although the match will come a few days too soon for centre-back Ledley King, returning from injury. Fulham caretaker boss Ray Lewington could turn to Chris Baird to replace Elliot Omozusi at full-back.

Wigan v Newcastle

Emile Heskey is on the mend after missing the draw against Fulham on Saturday, although he is unlikely to pass a fitness test for the clash against Newcastle. Mark Viduka is likely to keep his place up front for the Toon after his two-goal display against Derby, while Damien Duff suffered no adverse reaction to his first appearance of an injury-hit season and is likely to again be on the bench.

Sunderland v Man United

Sunderland go into the match with no new injury concerns from the defeat to Reading as Roy Keane welcomes Sir Alex Ferguson to The Stadium of Light. Manchester United hope to give long-term injury victim Park Ji-sung a spot on the bench, while Rio Ferdinand should also return to action. However, goalkeeper Edwin van der Sar will not feature until the new year as he battles to overcome a groin strain.

Everton v Bolton

Everton go into the northwest derby with a doubt over midfielder Tim Cahill, who picked up a knock in the defeat to Manchester United, although boss David Moyes could welcome back Mikel Arteta from injury. Bolton, who enter the match on a high after the 3-0 home win over Birmingham, could hand Heidar Helgusson a spot on the bench.

Derby v Liverpool

David Jones has recovered from the groin injury that kept him out of the draw at Newcastle, although the knee injury Claude Davis picked up in the warm-up at St James' Park is likely to keep him out. Rafa Benitez will rest players from the side that hammered Portsmouth, with fit-again Xabi Alonso and Ryan Babel pushing for starts.

Birmingham v Middlesbrough

Manager Alex McLeish has vowed to make changes for the clash after being disappointed by mistakes made in the defeat to Bolton. Skipper Liam Ridgewell is available after serving a one-match ban, while striker Mikael Forssell could be recalled to play alongside Cameron Jerome in attack. Fabio Rochemback is available for Middlesbrough after serving a one-match ban but Gary O'Neil (hamstring) is again a doubt.

Portsmouth v Arsenal (19.45)

Pompey manager Harry Redknapp could keep the same side that was beaten 4-1 by Liverpool, with Sean Davis faces a fitness test on his calf as he looks for a spot on the bench. Arsenal could hand Robin van Persie a first start since his return from injury.

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Man City-Blackburn (19.45 Thursday)

Manchester City boss Sven Goran Eriksson gave his players Christmas Day off in an effort to rest his stars ahead of the busy Christmas schedule. Vedran Corluka should return to replace Nedum Onuoha at right-back, while Michael Johnson faces a fitness test on his abdominal strain. Blackburn will be without Stephen Warnock and Robbie Savage, both suspended after picking up five bookings, although Christopher Samba returns from his one-match ban.

Alex Sharratt / Eurosport