Manchester United have suffered a blow after midfielder Darren Fletcher was ruled out for six weeks because of a knee ligament injury.Fletcher suffered the setback in Scotland's 1-1 draw against Croatia in midweek in a friendly at Hampden Park.

Manager Sir Alex Ferguson said: "It is a bad blow for us as Darren will be out for six weeks."

Louis Saha is also ruled out of Saturday evening's match against Aston Villa because of a hamstring problem.

Nani is doubtful because of thigh problem while Gary Neville and Mikael Silvestre remain sidelined through injury.

Kick-off at Old Trafford is 5.15pm.

United (from): Van der Sar, Brown, Ferdinand, Vidic, Evra, O'Shea, Ronaldo, Scholes, Nani, Anderson, Hargreaves, Carrick, Giggs, Park, Rooney, Tevez, Kuszczak, Foster.

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