Reuters - Tue, 27 Jul 20:43:00 2010
Australian Darren Cahill is widely believed to be Maclagan's likely successor but Murray said he would review the situation only after the August 30-September 12 US Open.
According to Murray's management team, the Scot made the decision "following a review of his coaching needs" and he was now focused on the US hardcourt season.
"I've had a great relationship with Miles over the past two-and-a-half years and I want to thank him for his positive contribution to my career," said world number four Murray.
"We have had a lot of success and fun working together."
Murray, 23, is competing in this week's LA Open at the LA Tennis Center where he is the top seed.
Maclagan added: "It's been a privilege to work with Andy as his coach and I'm happy to have played my part in his career.
"Andy is a great player and I know he will continue to have the success his talent and hard work deserves."
Murray, who had previously been coached by Briton Mark Petchey and American Brad Gilbert, has yet to win a Grand Slam title despite several close calls in recent years.
In the 2008 US Open final he was taken apart by Roger Federer and he fell to the Swiss maestro again in this year's Australian Open title match.
Earlier this month, Murray was beaten 6-4 7-6 6-4 by Spanish world number one Rafael Nadal in the last four at Wimbledon.
The Scot has not played a match since losing that match in south-west London.
Former clay-court specialist Alex Corretja remains part of his backroom team.