The 21-year-old Tuilagi, who sat out last weekend's win over Scotland, has recovered from an ankle injury and is available for selection for the mouth-watering clash in Dublin, which is already being billed as a potential title-decider.
Yet Stuart Lancaster's apparent midfield headache is not as difficult to solve as many would have you believe.
More from the Six Nations:
England vs Scotland: Where the game was won and lost
Kidney's keys in Cardiff victory