Match of the weekend: Tottenham v Manchester United
Yes, I know I'm picking a Manchester United game again, but this is one I always look out for as I supported Spurs as a kid.
Tottenham do not have a good record against United, but this is a real chance for Harry Redknapp to prove his side's top four credentials. They have had a blistering start to the season while the champions have not quite hit their stride yet. A lack of self-belief was a problem for previous Spurs outfits, but this time they should go into the game brimming with confidence.
Harry has got plenty of options up front, but I think he should stick with Robbie Keane and Jermain Defoe ahead of Peter Crouch.
Rio Ferdinand is likely to be making his comeback after a back injury, and if anything is going to test him it will be the movement and sharpness of those two.
I don't think either Ferdinand or Nemanja Vidic would mind going up against the more static Crouch, but when you think of how Samuel Eto'o gave them the runaround in the Champions League final with his movement, United could be vulnerable to Keane and Defoe.
Upset of the weekend: Liverpool v Burnley
This is a long shot of course, but there are reasons to believe Burnley might nick something from the game.
It is the kind of game that Liverpool have to win if they are to challenge seriously for the title - last season it was draws at home to the likes of Stoke and Hull that ultimately cost them.
However, as this game is wedged between the international break and the start of the Champions League group stage, you wonder if Rafa Benitez if going to rest some of his key players.
He has a particular problem in midfield, where Javier Mascherano and Lucas Leiva are both coming back from long trips to South America.
But if Benitez is serious about winning the Premier League he will play them against Burnley and if necessary give them the night off in Europe - which is after all an easy home game against Debreceni.
Burnley have fewer internationals so come into the game rested and in high spirits, but I think this will be decided by the approach Benitez decides to take.
Player to watch: Emmanuel Adebayor
There is no doubt the Manchester City striker will come in for stick from the visiting Arsenal fans, who rightly feel his attitude was poor during his final season at the Emirates.
The Togolese was never the same player after he filled his wheelbarrow with money signing a new contract at Arsenal.
Most Gooners were pleased to see him go but now, surprise, surprise; he is scoring goals again for City.
If he proves a point by scoring against his former club, it will just leave Arsenal wondering why he didn't do that last year. And they will be quick to point out to City's fans that they should wait until the second season to see what he is really like.
Under pressure: Phil Brown
Brown's Hull side travel to Sunderland, and both teams had a busy time in the transfer market.
However, Brown was unable to secure top targets like Alvaro Negredo and did not find an adequate replacement for Michael Turner, who is set to make his Sunderland debut against the Tigers.
At times it seems like Hull have just signed anyone who is available, and it will be a real test of Brown's managerial ability to see whether he can get the likes of Jan Vennegoor of Hesselink and Ibrahima Sonko to gel quickly.
It is a test that could decide whether Hull stay in the top flight or not.