The Montenegro star, 23, has scored 12 goals so far this season but will miss the next couple of weeks after suffering a thigh injury during the 2-1 defeat to Cagliari over the Easter weekend.
It’s not the most serious injury but the timing could barely have been worse. That defeat to Cagliari was enough of a blow as it meant Vincenzo Montella’s side slid six points behind third-placed Milan with eight matches remaining; if they lose on Sunday it could be a potentially fatal blow to their impressive revival under ‘L’Aeroplanino’.
Still, fourth place would not be a bad return on his appointment last season, given their travails under combustible Serb Sinisa Mihajlovic and the now infamous implosion of poor Delio Rossi. Famous wins over Inter (4-1) and Milan (3-1, away) prove that the Florence club are more than capable of mixing it with the big boys.
In Jovetic’s absence the main striking threat will be veteran target man Luca Toni, supported by Adem Ljajic, who clashed with both his previous Viola bosses but appears settled under Montella. Meanwhile Milan will look to their flamboyant young Italy strike pair, as Stephan El-Shaarawy and Mario Balotelli
But the real battle will be in central midfield, as reborn former Milan midfielder Alberto Aquilani goes toe-to-toe with ex-Fiorentina playmaker Riccardo Montolivo.
Italy midfielder Montolivo spent seven seasons at Fiorentina, captaining the side, before joining Milan at the start of this term.
Seen as a player who has never quite lived up to his early promise, the 28-year-old initially found the going tough as Milan's rebuilt team floundered, but he has become a driving force at his new club.
"I didn't realise he was so good, he can become the leader of this team for many years," team-mate Massimo Ambrosini said.
It remains to be seen what sort of reception he will get as he returns to his old club for the first time since his move last May.
"In life and in professions, relationships can break down and not always in an understandable and painless way for everyone," Montolivo wrote in an open letter to Fiorentina supporters after leaving the club.
"Although some see me as an enemy, I can only wish joy and satisfaction to Fiorentina, Florence, to my former comrades and all the people who work every day in the club with passion and dedication."
Aquilani, meanwhile, also lost his way after a disastrous move to Liverpool, but he appears to have put chronic injury problems behind him and – at the age of 28, just like Montolivo – has matured into a fine playmaker, scoring five and creating six this season.
The ex-Roma man has even got back into international contention, making next year’s World Cup in Brazil a realistic target.
But Florence is his bread and butter and, having declared his love for the Italy’s cultural capital, a big performance against one of his former employers would go some way to establishing both him and the club among Italy’s elite.