| Tuesday September 25 | ||||
|---|---|---|---|---|
| 25 Sep, 19:45 | Manchester City 2 - 4 Aston Villa | Etihad Stadium, Manchester | ||
| 25 Sep, 19:45 | Milton Keynes Dons FC v Sunderland | Stadium MK, Milton Keynes | ||
| 25 Sep, 19:45 | Crawley Town 2 - 3 Swansea City | Broadfield Stadium, Crawley | ||
| 25 Sep, 19:45 | Bradford City 3 - 2 Burton Albion | Coral Windows Stadium, Bradford | ||
| 25 Sep, 19:45 | Preston North End 1 - 3 Middlesbrough | Deepdale, Preston | ||
| 25 Sep, 19:45 | Southampton 2 - 0 Sheffield Wednesday | St. Mary's Stadium, Southampton | ||
| 25 Sep, 19:45 | Chelsea 6 - 0 Wolverhampton Wanderers | Stamford Bridge, London | ||
| 25 Sep, 19:45 | Swindon Town 3 - 1 Burnley | County Ground, Swindon | ||
| 25 Sep, 19:45 | West Ham United 1 - 4 Wigan Athletic | Upton Park, London | ||
| 25 Sep, 19:45 | Leeds United 2 - 1 Everton | Elland Road, Leeds | ||
| Wednesday September 26 | ||||
|---|---|---|---|---|
| 26 Sep, 19:45 | Manchester United 2 - 1 Newcastle United | Old Trafford, Manchester | ||
| 26 Sep, 19:45 | Queens Park Rangers 2 - 3 Reading | Loftus Road, London | ||
| 26 Sep, 19:45 | Norwich City 1 - 0 Doncaster Rovers | Carrow Road, Norwich | ||
| 26 Sep, 19:45 | Arsenal 6 - 1 Coventry City | Emirates Stadium, London | ||
| 26 Sep, 19:45 | Carlisle United 0 - 3 Tottenham Hotspur | Brunton Park, Carlisle | ||
| 26 Sep, 20:00 | West Bromwich Albion 1 - 2 Liverpool | The Hawthorns, West Bromwich | ||