| Pos. | Player | Goals | Team |
|---|---|---|---|
| 1 | Oscar Cardozo | 26 | Benfica |
| 2 | Radamel Falcao | 25 | FC Porto |
| 3 | Liedson | 13 | Sporting Lisbon |
| 4 | Cássio | 12 | União Leiria |
| 4 | Edgar Silva | 12 | CD Nacional |
| 4 | Djalmir | 12 | SC Olhanense |
| 7 | Javier Saviola | 11 | Benfica |
| 7 | Meyong | 11 | Sporting Braga |
| 9 | William Arthur | 10 | (FC) Paços of Ferreira |
| 10 | Modou Sougou | 9 | Académica Coimbra |
| 10 | Keita | 9 | Vitória Setúbal |
| 12 | Silvestre Varela | 8 | FC Porto |
| 12 | Kléber | 8 | CS Marítimo |
| 12 | Alan | 8 | Sporting Braga |
| 15 | Christian Pouga | 7 | Leixões SC |
| 15 | Ernesto Fariàs | 7 | FC Porto |
| 15 | Hugo Morais | 7 | Leixões SC |
| 15 | Lima | 7 | Belenenses |
| 19 | Yannick Djalo | 6 | Sporting Lisbon |
| 19 | João Tomás | 6 | Rio Ave (FC) |
| 19 | Maykon | 6 | (FC) Paços of Ferreira |
| 19 | André Castro | 6 | SC Olhanense |
| 19 | Djalma | 6 | CS Marítimo |
| 19 | Baba | 6 | CS Marítimo |
| 19 | Carlão | 6 | União Leiria |
| 26 | Weldon | 5 | Benfica |
| 26 | Nuno Assis | 5 | Vitória Guimarães |
| 26 | Rui Miguel | 5 | Vitória Guimarães |
| 26 | Jean-Paul Yontcha | 5 | Belenenses |
| 26 | Paulo César | 5 | Sporting Braga |
| 26 | Bruno Alves | 5 | FC Porto |
| 26 | João Moutinho | 5 | Sporting Lisbon |
| 26 | Matheus | 5 | Sporting Braga |
| 26 | Ángel Di María | 5 | Benfica |
| 26 | Andrezinho | 5 | Vitória Guimarães |
| 26 | Hulk | 5 | FC Porto |
| 26 | Mehdi Kerrouche | 5 | Naval |
| 26 | Henrique | 5 | Vitória Setúbal |
| 39 | Pablo Aimar | 4 | Benfica |
| 39 | Cristian Rodríguez | 4 | FC Porto |
| 39 | Przemyslaw Kazmierczak | 4 | Vitória Setúbal |
| 39 | Zé Manuel | 4 | Leixões SC |
| 39 | Miguel Fidalgo | 4 | Académica Coimbra |
| 39 | William Tiero | 4 | Académica Coimbra |
| 39 | Valdomiro | 4 | Vitória Guimarães |
| 39 | João Aurélio | 4 | CD Nacional |
| 39 | Éder | 4 | Académica Coimbra |
| 39 | Wíres | 4 | Rio Ave (FC) |
| 39 | Hugo Viana | 4 | Sporting Braga |
| 39 | Roberto | 4 | Vitória Guimarães |