Bolt will be one of a dozen Olympic champions competing over the three-day event between July 26-28, which forms part of the Diamond League series. He will race in the 100m on July 26, then run the 4x100m relay the following evening.
Other Olympic gold-medallists confirmed for the event include the likes of Jessica Ennis and Sally Pearson, who will contest the 100m hurdles, as well as world-record 110m hurdles champion Aries Merritt, and 400m winner Kirani James.
Mo Farah and Greg Rutherford will also be on the bill, but it is Bolt’s name which has grabbed the headlines – the Jamaican has not competed on these shores outside the Olympics since 2009.
“I’m looking forward to coming back to the UK, especially with it being a year since winning three gold medals in the Olympic Stadium. The crowd were amazing at the Games, and I hope they will be out again in their numbers at the end of July.”
Bolt's absence from the UK has been partly due to Britain's tax laws which could have seen him give up a share of his appearance or prize money and endorsements.
An exemption for "non-residents" is now in force and Bolt said he was relishing the chance to play a part in what is being dubbed the "Anniversary Games."
Bolt won the 100m and 200m in London and then helped Jamaica win the 4x100m relay in a new world record.