Heading into the final day in Nove Mesto, Czech Republic, Norwegian Berger had four golds and a silver to her name as she had stormed past everyone in her way.
And in the 12.5km mass start Berger made it six medals from a possible six, becoming the first biathlete to complete such a feat, as she collected silver.
But the main celebrations belonged to Belarus' Domracheva who put a poor season behind her to take gold in 35:54.4 minutes, 8.7 seconds seconds ahead of Berger.
This was Domracheva's second world title, adding to her pursuit title from last year's event in Ruhpolding.
And there was also plenty to shout about for Poland's Monika Hojnisz who finished third in her first-ever mass start, having never even qualified before in the World Cup.