Shipulin emulated his sister, Anastasiya Kuzmina, by winning the opening sprint in Italy and, while he was made to work hard to do so, victory in the pursuit was easier to come by.
The 25-year-old missed two targets in the range but it was to matter little as he clocked a winning time of 31:24.2minutes with Slovenian Jakov Fak second and Daniel Mesotitsch third.
Given bib No.1, Shipulin built up a healthy advantage early on and shot clear first time and led by over 42 seconds from defending World Cup champion Martin Fourcade at one stage.
That was halved after Shipulin missed a target on his second shoot and dropped to less than 15 after he repeated the trick on his third visit to the range in Antholz-Anterselva.
Fourcade then clawed even more time back but Shipulin was clear with his last shoot and raced away to victory as Fak came up through the field to deny Mesotitsch second.
Defending World Cup champion Fourcade had to make do with fourth to take his points tally at the top of the overall standings to 645, Emil Hegle Svendsen, who was fifth, second with 583.