The Welsh flyweight secured a classy points win over Ivan Ilntyskyy but with Joe Ward the only other British Lionheart to taste victory, the hosts lost 3-2 at York Hall in London.
Britain headed into the clash on Friday night knowing that they had already secured a place in the quarter-finals, where they will now face Mexico.
But they will be disappointed to lose their undefeated home record, despite running the star-studded Ukrainians close and Irish light-heavyweight Ward winning on points against Denys Solonenko.
Heavyweight Joe Joyce lost to London 2012 gold medallist Oleksandr Usyk, Fred Evans, who won silver in the capital, was beaten by Dmytro Mytrofanov in the middleweight bout while Sam Maxwell lost to two-time Olympic champion Vasyl Lomachenko.
Lomachenko has lost just once in 300 fights and, despite tasting defeat, Maxwell admits he can hold his head after running him close.
"I'm disappointed to have lost but I proved to myself that I belong up there in world class," Maxwell said.
"There were people who thought I'd done myself proud just by being in the ring with Lomachenko, but I've gone ten rounds with him and definitely proved a lot to a lot of people.
"There is no doubt Lomachenko is the best amateur boxer in the world and he proved that again in there tonight. But I wasn't a million miles away and that will give me a lot of confidence."