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Robin van Persie's brace saw Manchester United through to a 2-1 win at CFR Cluj-Napoca in their Group H clash at the Dr. Constantin Radulescu Stadium.
It took a late flurry of goals for holders Chelsea to look comfortable in beating Nordsjælland 4-0 at Parken Stadium.
Georgios Samaras headed home a dramatic winner as Celtic's 3-2 win at Spartak Moscow ended a 26-year wait for a Champions League away win.
Alexis Sanchez and Cesc Fabregas were on target as Barcelona convincingly beat Benfica 2-0 in their Group G encounter in Lisbon.
BATE Borisov pulled off a huge Champions League shock, producing a classic display of counter attacking to beat Bayern Munich 3-1 in their Group F encounter in Minsk.
Leonardo Bonucci scored a superb goal as Juventus escaped with a point as they drew 1-1 with Shakhtar Donetsk in Group E.
A brace from Jonas gave Valencia a 2-0 Group F win at home to Lille.
Ruben Micael’s first half goal and a fine injury-time effort from Alan were enough to give Braga a 2-0 victory in Istanbul and leave Galatasaray bottom of Group H.