As a preamble to Bell's press conference, it fell to an England and Wales Cricket Board spokesman to confirm wicketkeeper Prior has torn his calf and will miss the tourists' final Ashes warm-up match against an Australian Invitational XI, scheduled to start on Wednesday.
Pietersen's fitness, meanwhile, is being monitored with the batsman only taking a small part in England's indoor nets and drills at the SCG on Monday.
England were confined to indoor training due to the weather in Sydney, where it has rained for much of the past 24 hours and is expected to carry on for another day at least.
It was hardly the welcome they would have wanted in Australia's biggest city, having spent much of the past week shivering and sheltering through a scheduled four-day fixture in Hobart which was more than halved in duration by bad weather.
There is more than a crumb of comfort in a favourable prognosis for Pietersen's problem right knee - after a scan and cortisone jab in Melbourne - and, of course, it was Bell's duty to accentuate the positive.
An unexpected opportunity for Jonny Bairstow, deputising for Prior when it seemed he might spend much of this tour carrying drinks and other requirements for his team-mates, is one such.
"I suppose it's not ideal, but it gives a good opportunity to Jonny Bairstow," Bell said of Prior's absence this week.
"We've seen in the past how important it is to get the whole of the squad playing cricket before the series starts - because you just never know, with five Tests to come."
Bairstow, for example, cannot yet know whether his centre-stage role will extend to the first Test in Brisbane in 10 days' time, but given the nature of Prior's injury, that must rate a significant possibility at this stage.
The ECB spokesman said: "Matt Prior has been ruled out of the tour game, starting on Wednesday, with a low-grade tear of his left calf.
"He will continue his rehab and recovery with a view to being fit for the first Test match."
Bell added: "It's disappointing ... Matt is a key part of our success over the last few years, and obviously we want him to recover as quickly as possible."
As for the Gabba, the party line appears to be cautious optimism.
Bell delivered it: "There's still a bit of time.
"Matt's got himself in fantastic condition for this tour, and he'll be very good with his rehab.
"I've got every faith that he'll be fully-fit for Brisbane.
"But it's good for Jonny, in this game, to get out there with the gloves on in an England shirt."
Pietersen's diversion to Melbourne for treatment and an updated appraisal of the injury which kept him out for three months earlier this year, and almost required surgery, appears to have had a good outcome.
Asked for his fellow batsman's chances of playing this week, and how Pietersen is feeling, Bell said: "Really well.
"I don't know the XI. But I'd have thought he's definitely up for selection, and would have thought he'll play."
Even so, none of the above adds up to the seamless preparation England had for their last campaign here, which ended in a historic 3-1 series victory.
Bell is not trying to pretend otherwise, accepting England's Ashes build-up has not gone entirely according to plan so far but insisting that will not put the tourists off.
"A little bit. That's out of our control really," he said.
"If we focus too much on that, it can get in your 'bubble' a little bit.
"I don't think we're always going to get what we had last time here. Obviously, things went incredibly well (then).
"With the weather we've had, to have four hundreds out of two batting innings is a fantastic start to the tour ... so that's a good sign for us."
As coach Andy Flower pointed out in Hobart, it is in any case folly to try to recreate the past, and England, under his guidance, will not be tempted down that route.
"We've got what we've got. I don't think it worries too many people," said Bell.
"We've got a lot of experience in the team that can cope with that.
"Everyone will be 100 percent ready for Brisbane, no doubt."
Whether that applies to Prior, or Pietersen, remains open to question.
England (v Australia Invitational XI in Sydney, from): AN Cook (Captain), MA Carberry, IR Bell, KP Pietersen, JE Root, GS Ballance, JM Bairstow (wkt), SCJ Broad, GP Swann, ST Finn, CT Tremlett, IJL Trott, JM Anderson, WB Rankin