Kaneria failed on Tuesday with his appeal against a lifetime ban imposed by ECB, and effective worldwide, having initially been found guilty by the national board of corruption while playing for Essex in 2009.
The 32-year-old former Pakistan leg-spinner was banned a year ago, after being described as "cajoling and pressurising" his ex-Essex team-mate Mervyn Westfield into accepting cash in return for trying to concede a set number of runs during a Pro40 match.
On Tuesday, an ECB appeal panel of the cricket discipline commission upheld Kaneria's sanction - while Westfield, who was imprisoned for his part in the affair, had his five-year playing ban varied. The ECB's latest ruling states that Westfield may return to club cricket from next April - three years before his ban from the professional game is due to be completed. Any return must, however, be made on the proviso he adheres to an anti-corruption education programme.
Kaneria has repeatedly denied all involvement in the corruption case, but his appeal against two ECB charges has now twice failed on appeal.
Clarke responded last night by urging Kaneria to "come clean". Only last week, former Pakistan captain Salman Butt admitted to spot-fixing charges he had previously strenuously denied but for which he was criminally convicted in a separate case relating to no-balls being bowled in a Lord's Test in 2010. During Westfield's criminal trial last year, he named Kaneria as the figure who induced him into accepting £6,000 from a bookmaker to under-perform in the 2009 match.
Clarke said in a statement: "ECB welcomes today's decision to uphold the life ban imposed on Mr Kaneria for his corrupt activity. The appeal panel's findings in this case clearly confirm the disciplinary panel's finding that Mr Kaneria acted as a recruiter of potential 'spot-fixers' and used his seniority and international experience to target and corrupt a young and vulnerable player."
Kaneria, Clarke believes, should now do the decent thing.
"It is high time Mr Kaneria came clean about his involvement in these corrupt activities and stopped misleading the Pakistan cricket fans and wider public with his empty protestations of innocence," he added.
"We urge him to apologise publicly for his past actions and to start the process of redeeming himself by supporting the Pakistan Cricket Board's anti-corruption initiatives and assisting the police and law enforcement bodies in the Asian sub-continent with the vital job of exposing and cutting off the primary source of cricket corruption - namely the illegal bookmakers such as those referred to in the appeal panel's findings in this case."