But the left-hander hopes his flexibility in Australia's batting order will save him from being dropped for next week's third Test.
Back in his old opening spot on Friday, Hughes recovered from a scratchy start to post 84 in the tour match against Sussex.
"I don't mind where I bat but when you do move from one to six, mentally it can be frustrating," Hughes said. "At times it can be tough to get your head around the different positions but you've just got to get on with it.
"It was different going out opening. It's something that I'm very comfortable with, opening the batting. I've done it for a number of years."
The 24-year-old is under fierce pressure to keep his place for Australia's must-win Test against England at Old Trafford following his poor contribution at Lord's last week.
Batting at number four, Hughes was out for one in both innings as Australia wilted under the pressure of facing England's attack.
"When you lose Test matches there are obviously changes. When you lose it is not a good thing. It is about finding the right balance. You don't know what they (the selectors) are going to do," he said.
"Overall I feel confident and hopefully I'll be in that third Test side when it's selected."
With David Warner hitting 193 for Australia A against South Africa A this week, Hughes could be the one to make way should selectors opt for more top-order changes.
"It's about opportunity," he said. If you do get one position you do want to nail it down. I haven't nailed it down.
"I think there's always competition and that's a good thing. It's great to see Davey score a big 190 for Australia A and I thought we all batted quite well here.
"The last Test match obviously didn't go to plan personally but it's only one game. I felt like the first Test match, the 81 not out I scored (at Trent Bridge) was probably one of the better innings I've scored in the international arena."