McGurk was substituted during the closing minutes of last weekend's vital 2-1 victory over fellow promotion chasers Brentford and is facing two weeks on the sidelines with a hamstring injury.
Akpa-Akpro - recently back from a lengthy absence due to a broken metatarsal - sustained a heavy blow to the ribs in the match and, although X-rays revealed no fractures, he is unlikely to feature against the Robins.
"There are one or two doubts - McGurk and Akpa Akpro are the biggest," Rovers boss Ronnie Moore told his club's official website.
"I'd say McGurk will miss it and Akpa Akpro is 90 per cent missing it. We're not short, but we'll miss the Akpa Akpro pace up front.
"Adam is probably going to be out for a fortnight with a hamstring injury and Akpa Akpro needs a week to get over the rib injury he got."
Captain James Wallace is still missing in midfield due to a medial knee ligament injury.