The Bantams have had a fine week after disposing of Arsenal in the Capital One Cup on Tuesday and then being reinstated to the FA Cup the following day, but Phil Parkinson's focus now returns to their promotion campaign.
The victory over the Gunners came at a cost as Wells suffered a knee injury and Atkinson picked up a hip problem.
Both men will be assessed ahead of kick-off, with Parkinson not willing to take risks with their fitness.
Winger Kyel Reid (groin) and striker Zavon Hines (ankle) are making good progress but are unlikely to return before Christmas, while Andrew Davies (knee) is not expected back for a month.
Fellow defender Luke Oliver (Achilles) is out for the rest of the season.