Baptiste missed out on the dramatic safety-clinching victory over Derby and the defender's tight hamstring will be assessed.
Isaiah Osbourne will hope to feature having missed out on the matchday squad on his return from suspension last weekend, while youngster James Caton could make his professional debut and feature at some stage in midfield.
Ludo Sylvestre scored a late winner against Derby, his third goal in five matches having also settled the 1-0 win over Burnley at Bloomfield Road last month, and the French midfielder is keen to sign off in style.
He told Blackpool's official website: "We know that Bolton is still an important game because it is a derby match and we always want to play well in that type of game away from home.
"We have to have a good game and then we can perhaps relax after it."