Caley are trailing their third-placed Dingwall neighbours by one point with both sides looking to secure a top-six place in the Clydesdale Bank Premier League for the first time and possibly a place in Europe.
Enthusiastic Inverness manager Butcher is looking for a full house to witness the battle.
He said: "I think this is the biggest (derby) without a shadow of a doubt. It stands alone.
"It should be an incredible atmosphere and anyone who hasn't got a ticket yet should really come among because both sets of players have had brilliant season, they are bang on form and they are going to have a right go at each other.
"I think a win would secure either team a place in the top six and that is history. People should come along and see that.
"We want to be the ones who make the history first and get there."