Buxton was sent off in Saturday's derby win over Barnsley for a second yellow card offence and will sit out a one-game ban, so Martin Taylor will come into contention for a recall.
Seyi Olofinjana and fellow midfielder Stuart Holden made their debuts after joining on loan last week from Hull and Bolton respectively, and manager Dave Jones must decide if both are capable of playing two games in four days.
Giles Coke, fit again after a foot injury, replaced Holden in the second half on Saturday, while Rhys McCabe, Kieran Lee, and David Prutton provide Jones with extra options in midfield.
Jermaine Johnson is in contention to start. He returned to the bench following international duty with Jamaica, but fellow winger Michail Antonio (groin) is out for the rest of the season.