The Shakers would definitely drop down at the end of the season if Latics pick up a much-needed victory, but they may have to do so without Byrne.
The former Scunthorpe man was replaced by James Tarkowski before half-time in Tuesday night's 2-0 defeat to Preston following a groin problem, but Johnson is hopeful he can be included.
"It's just his muscle spasmed in the groin," the manager explained. "Hopefully he'll be okay. It (the substitution) was a precautionary measure, really."
Top scorer Jose Baxter misses out after collecting his 10th booking of the season at Deepdale and activating a two-match ban.
Youngster Chris Sutherland suffered his latest setback in a season beset by injuries when he sustained a hamstring injury playing for the reserves in midweek.