QPR loanee Andrade suffered a recurrence of the problem he picked up in the 3-0 defeat to Bradford, while striker Grant eventually limped off having picked up a knock in the first half.
The duo will undertake fitness tests in the build-up to kick-off and Ainsworth may have to recall himself having inspired his side to a 2-1 victory at Plainmoor in the second half.
The Chairboys' player/manager, who is yet to decide whether to hang up his boots at the end of the season, has made 19 appearances in the current campaign to date and could feature again on Saturday.
