Defender Harry Hooman, who last featured in October, remains Town's only absentee after an infection halted his return from a long-term foot injury.
Otherwise, manager Mark Yates boasts the same squad who finished the regular League Two season with last Saturday's goalless draw against Bradford.
Striker Paul Benson made his return from an ankle ligament strain as a second-half substitute against the Bantams and is again in contention for involvement at Sixfields.
Ahead of the game, Town boss Yates told reporters: "I'm not too keen on telling people my team but we'll pick the team we think that's right to go down to Northampton.
"It's going to be a really tough place. It's going to be a physical bombardment and a battle from their set-pieces, which are a fantastic weapon for them.
"We've got to deal with them. We've got to play our way and we'll have to deal with crowd. They'll have a big, noisy crowd behind them. I've been there when it's been a decent following there and they really get behind the team.
"So we need our supporters and we need the players to embrace the situation, embrace the challenge and really have a go at it."