Coke sustained a foot injury in the midweek defeat at Watford and was replaced just before half-time by Jose Semedo.
Semedo is likely to return to the starting line-up if Coke fails to make it.
Defender Reda Johnson remains sidelined after missing the last six matches with an ankle injury, but manager Dave Jones has no other new injury or suspension worries.
Striker Leroy Lita, on loan from Swansea, and winger Jermaine Johnson were both second-half substitutes in midweek and are pushing for recalls, while midfielder Rhys McCabe, defender Martin Taylor and forward Gary Madine are all hoping to be involved.
The Owls are two points above the relegation zone and have lost their last two matches.