The Shrimpers saw last season's promotion dreams crushed in the play-off semi-finals by a Crewe side who went on to clinch victory at Wembley over Cheltenham and seal promotion from npower League Two.
Centre-back Cresswell was not part of Southend's ranks for the heartache, joining from Rotherham last summer, but he insists the Essex club are looking to get their own back in what will be his first appearance at the national stadium.
"I think that's just in the back of any footballer's mind, any competitive person, if someone has one over you then the next thing you want to do is get them back. That's just human instinct," he told Press Association Sport.
"As a football club, we owe Crewe a good hiding, they denied this club from going to Wembley last season. I think now we've made that step to get to Wembley this season, we're going there to win it.
"That's the main thing everyone needs to realise - yes, well done getting there but it's no good going there and losing, it's a place where you want to win."
Cresswell stresses it is business as usual at Roots Hall after Phil Brown replaced sacked boss Paul Sturrock less than two weeks ago, with the Scot subsequently declining chairman Ron Martin's unprecedented offer of making a stunning one-game return for the Trophy final.
Sturrock will instead be one of over 31,000 Southend fans attending the club's first-ever cup final at Wembley.
Cresswell added: "It will be weird, thinking about it now, the new gaffer's going to be in the dugout and the old gaffer's going to be in the stands.
"But I can guarantee that as soon as the whistle blows the only thing I'll be concentrating on is what happens in between the white lines."