Striker Bowditch (groin) was a doubt ahead of last Saturday's game against Colchester while winger Powell (hamstring) would have missed the trip to Essex, which was postponed due to snow.
Luke Chadwick has also resumed training following a hip flexor problem and the winger could come back into the squad.
Goalkeeper David Martin (back) and captain Dean Lewington (knee) look set to remain on the sidelines, though.
Izale McLeod could join them. He is a new concern after sustaining an injury in training this week and the striker will be assessed ahead of the game.
One player who will definitely miss out is Antony Kay. The centre-half will begin a three-match suspension following his red card in the defeat at Crewe on March 19.