Dreyer has been given the added responsibility after Graham Westley departed on Wednesday following a run of seven matches without a win.
The 49-year-old has Bailey Wright available after a one-match suspension. The Australian defender was sent off in the 1-0 defeat to struggling Colchester.
However, North End have concerns over a number of unidentified players who sustained knocks in Westley's final game, the 3-1 defeat at Yeovil, and Dreyer will have to wait on late fitness checks before naming his team.
Stuart Beavon, Joel Byrom and Jack King all remain on the sidelines along with John Mousinho (hamstring) and Scott Laird (broken leg).
On-loan Norwich goalkeeper Declan Rudd was handed a debut against the Glovers and may retain his place.