Keith Curle's men have not lost an away game this season and the former Ipswich trainee knows what a threat the visitors, six points above 12th-place Yeovil, will pose.
But he believes their clean sheet and professional display against Wanderers was a helpful warm-up.
"Tuesday was a good game to prepare for Notts County," Upson told Press Association Sport. "They are a good team aren't they? It will be a tough game but it was good to get out there and get playing after 10 days or so without a game and it was definitely a good warm-up for that."
That 10-day gap, which came because of Yeovil's FA Cup elimination at Preston in the FA Cup first round, gave manager Gary Johnson a chance to work on a few things with his team.
Upson added: "We were in most days and we did a bit of karate and a few different things, a bit of team-bonding. But it was all hard work and hopefully it will all pay off."
Since returning from his four-game suspension for a red card at Deepdale, Upson has gone straight back into Johnson's starting line-up and capped a fine performance against Wycombe with a header, his first goal from inside the box and his third of the campaign.
"I am really enjoying being back in the team and it was nice to get a goal on Tuesday," he said. "But we won and that is the main thing for me.
"My aim is to get more goals now and kick on. I have set myself a goalscoring target but I'll keep that to myself. Things are going well though."