Twenty years ago another central defender, Gary Pallister, scored his first of the season in the same goal in the penultimate match of Ferguson's first title-winning season.
Now Ferdinand has done the same in Ferguson's 13th and last championship of a staggering career that will end for good at West Brom next Sunday.
Indeed, it was the first time Ferdinand had found the net since 2008, although on such a grand occasion as this, it was fitting United should get a late - if not quite 'Fergie Time' - winner from someone who has worked with the Scot since his arrival from Leeds in 2002.
Javier Hernandez, replacement for the dropped Wayne Rooney, chipped an early effort against the bar that had been supplied by Robin van Persie.
And it was Hernandez who drove home his 17th goal of the season to put the hosts ahead after Ashley Williams had made a hash of trying to clear Van Persie's free-kick.
It was all slightly unfortunate for Swansea, the obligatory guests at a party no one wanted to speak to them at, other than to lambast them if they threatened to get in the way.
And that was exactly what they did five minutes into the second half, when United found themselves under pressure, failed to clear a corner and allowed Nathan Dyer to drill over a low cross from the right.
It hardly needed saying Michu would be the danger-man in such situations. United did not pick him up, though, and he duly turned home his 21st goal of an incredible debut campaign.
But all this occasion needed was a United at the end. Ferdinand supplied it, allowing Ferguson to leave Old Trafford in the most appropriate manner possible.