A fantastic goal from Demba Ba, and an equally impressive save from Petr Cech, put an end to United's Cup hopes on Monday as Rafael Benitez enjoyed a rare victory against his old enemy at Stamford Bridge.
The 1-0 defeat dashed Ferguson's hopes of lifting his first FA Cup in nine years, but the Scot knows the disappointing defeat will be all but forgotten if United beat their neighbours City at Old Trafford on Monday night.
Victory over their bitter rivals will put the Red Devils 18 points clear at the top of the Barclays Premier League with seven games left.
A miracle would then be the only thing to prevent United from clinching their 20th title against Stoke or West Ham in the following weeks.
"We will kick on," the United boss said. "It was disappointing (to lose against Chelsea), of course, but we have to forget all about it and move on to the game against City next Monday.
"We are in a good position obviously and I think a positive result for us on Monday will just about seal the title for us."