United needed two games to ease past West Ham at the third-round stage and with Dimitar Berbatov eager to impress on his return to Old Trafford, it is not entirely beyond the realms of possibility that Fulham could force the Red Devils into a second game as well.
That would almost certainly be played on the weekend reserved for the fifth round, in between the two Champions League ties with Real Madrid, with a fixture backlog looming should United eventually make it through.
Little wonder therefore Giggs wants progress towards a first FA Cup triumph since 2004 to be made with clinical efficiency.
"Win the FA Cup was one of my first memories as a United player," he said.
"The competition was huge for me growing up and still is and we have so many players here who are desperate to win it.
"You want to be challenging on all fronts given the strength in depth we've got. But we are quite keen to avoid a replay because we've got a lot of games coming up.
"We realise this will be a difficult game - Fulham did well when they came to Old Trafford earlier in the season and we're going to have to be at it right from the start."