The former Rangers and Blackpool man missed the 3-0 victory at Morecambe on Saturday with an ankle injury which looks like being worse than first suspected.
A club statement confirmed that the Scot is likely to be sidelined for a few weeks, missing the chance to take on a side he excelled against earlier in the campaign.
Gow scored two memorable goals in a 3-0 win at The Crown Ground back in August but he will be missing against Leam Richardson's men along with John O'Flynn, (hamstring) Liam Sercombe (ankle) and Matt Oakley (thigh).
While the Grecians recorded their tenth away win of the season last weekend they have won just once at St James Park since November.
