The Jambos right-back, 26, has been out since rupturing his cruciate knee ligament during an indoor training session last April but has almost completed his rehabilitation.
"Jamie has come through two under-20 games, he played 60 minutes in one and 75 in the other and looked really good," said Locke.
"He has trained for a number of weeks so he will come into contention for the squad for the weekend."
Locke's own career was disrupted by injury and thus he empathised with the former Kilmarnock player's frustration during his spell on the sidelines.
He said: "I know exactly what he has gone through. Unfortunately for me I was in the same position.
"It is a nightmare. You just want to get out on the pitch.
"He has had a couple of niggles which you will get being out as long as he has, but he has worked really hard and hopefully he will get his rewards before the end of the season in terms of he might get a few first-team games.
"But he has been out for a long time so to do anything silly now would be stupid of him.
"I think it is important that he gets a few games before now and the end of the season, gets a good pre-season behind him and hopefully we will see the best of him at the start of next season."