Saints have not won any of their three matches since the Argentinian replaced Nigel Adkins at the helm and face the unenviable task of looking for a first victory against Manchester City.
It is a match in which Lallana could make his first start since December 8, having suffered a knee injury in the 1-0 defeat of Reading at St Mary's.
That was Southampton's last home victory and Lallana is hoping to make up for lost time against the reigning champions.
"I have been itching to get back now the whole time," he told Press Association Sport.
"I've been there or thereabouts the last three or four weeks and I've made a couple appearances off the bench.
"I am fully fit and eagerly hoping to get some time from the start, whether I do, we will find out on Saturday.
"I was injured when Alan Pardew left the club and Adkins came in so I've experienced similar to this.
"It was frustrating because you want to get out there and prove to him your worth, really.
"He has been great and the language barrier is not an issue. You communicate fine and his assistant Jesus Perez, Miguel D'Agostino and goalkeeping coach Toni Jimenez can all speak English well.
"It is great and I am so far thoroughly enjoying my time under the gaffer."