Green was denied the chance to play against Premier League champions Manchester City in the FA Cup fifth round on Sunday after suffering an ankle injury in the build-up to the game.
"Greeny went over his ankle," said under-pressure Leeds manager Neil Warnock, who reported no new problems following the defeat at the Etihad Stadium.
"He was desperately disappointed. He asked if he could have a late fitness test, but I said no. I would rather him be fit for Wednesday, and I would think we will have him back for then."
Warnock also revealed he made his half-time substitutions against City with Wednesday's game in mind. Both Michael Brown and Ross McCormack were replaced at the break in Manchester.
"I wanted to keep Browny and Ross for Wednesday," Warnock said. "Browny is doing brilliant at the minute and he's played a lot of football, and Ross is obviously a big player for us and I want him for Wednesday."
Paddy Kenny is likely to return in goal against Blackpool after Jamie Ashdown was once again used in a cup competition.