The Hoops are 2-0 down from the game against the Kazakh champions in Astana and Shakhter's Russian coach has been quoted as saying they would "score a pair of goals" in Glasgow to take them through to the group stages.
At Celtic's training complex in Lennoxtown on Tuesday morning, Hoops manager Lennon hit back, saying: "We know we have to win the game by three goals.
"If they score we need to score four, if they score two - according to their manager - then we need to score five.
"I think it (their confidence) is very dangerous and it can always come back to bite you.
"This is a two-game tie and it is disrespectful to my team as well.
"I don't need to motivate my players for this game but if they want to keep talking the way they are doing then that's fine."
Lennon confirmed that midfielder Beram Kayal will miss the game with a groin complaint that will keep him out for a fortnight.
The Israel international picked up the injury in Saturday's 2-2 home Scottish Premiership draw with Inverness and while Dutch defender Virgil van Dijk was troubled with a hamstring at the weekend, he will be fit.
Kris Commons also missed the match with a groin strain and will not train but Lennon is not ruling him out.
He said: "We are hoping that four of the five who missed Saturday will take part in training today (Tuesday) but whether they finish the session is another thing."