Cook, who left Stanley in October to take over at the Proact Stadium, has been without the experienced Lester for the last three matches due to suspension.
The eight-goal striker, 37, will be fresh and raring to go after sitting out the busy Christmas schedule and could start at the Crown Ground.
While Lester returns from suspension, on-loan Hull defender Conor Townsend begins a ban after the youngster was shown a straight red card during the 1-1 draw against Morecambe on Saturday.
Marc Richards was only fit enough for a place on the bench against the Shrimps after missing the Boxing Day win over York with the hamstring problem that forced him off just before half-time in the defeat at Southend on December 21.
He may join Lester in pushing for a recall on New Year's Day, while fellow strikers Scott Boden and Luis Boa Morte, defender Neal Trotman and midfielders Craig Clay and Mark Randall are also options for Cook.