Success has followed wherever two-time Champions League-winning boss Mourinho has been - at Porto, in his first spell at Chelsea and at Inter Milan - but a third Premier League title, eight years after the last, would be treasured.
Speaking on Chelsea's arrival in Jakarta for the third and final match of the Asia tour, Mourinho said: "I always say that the best trophy you have is the last (most recent) one. (But) if we win something important with this group, it will be the best for many reasons."
One of those reasons is the competition in the top-flight, with Mourinho believing defending champions Manchester United, Manchester City, Arsenal, Tottenham and Liverpool are all rivals for the title.
City have spent most lavishly this summer, recruiting Jesus Navas, Fernandinho, Alvaro Negredo and Stevan Jovetic, to bolster their ranks after relinquishing the Premier League title to United last term.
"I think they've bought very, very well," Mourinho said. "They have the money to buy, but they have also the knowledge; they have people in the club who know a lot about football.
"They are players at the top of their careers, experienced but still young.
"If you see their age, their maturity, they are in the perfect moment of their career to go to England - no need for adaptation, no need of work to learn the project."
United and Arsenal are still bidding to add to their squad, but Chelsea's is almost complete.