The Owls are on a six-match unbeaten run in the league and sit two points clear of the relegation places.
But Palace have already ended an unbeaten run of theirs this season. The 2-1 win at Selhurst Park in September ended Wednesday's 19-game run, that had stretched back to February 2012.
Jones expects to have a full squad at his disposal as they look to avoid a repeat, though he did admit that "three or four" of his players were struggling with knocks and would be assessed ahead of the game as a precaution.
Defender Reda Johnson could return to the squad after overcoming an ankle problem that has seen him miss the last three games.