Midfielder Walton was forced out of the midweek home win over Crewe with a nerve problem in his leg but has an outside chance of returning to contention.
His replacement Andy Monkhouse is likely to return to the starting line-up if Walton fails to make it.
Horwood struggled towards the end of Tuesday night's win with a tight calf muscle but lasted the full 90 minutes and is expected to resume in defence.
Manager John Hughes has no other new injury or suspension problems and is unlikely to make any unforced changes to his side.
Midfielder Antony Sweeney (knee) is still sidelined and teenage defender Jordan Richards (knee) is out for the rest of the season.