The Seagulls manager has urged his promotion-chasing men to seal a top-six spot against Leeds next week and avoid any last-day nerves against Wolves.
Will Buckley put the Seagulls ahead in the ninth minute after cutting inside and guiding a sweet finish into the top right-hand corner, before Matthew Upson bundled his first Brighton goal over the line mid-way through the first half.
Andrea Orlandi, David Lopez and Ashley Barnes (2) all found the net as Brighton hit six, and an own-goal by Dean Hammond was Blackpool's only consolation on a miserable afternoon for Paul Ince's men.
Poyet said: "It's not done yet and we need to keep going. We will want to finish it next week at Leeds and not have it still undecided going into the final game.
"I was hoping when it was 3-0 at half-time that we wouldn't blow it and lose 4-3 because that could have been the end for us.
"But we are looking good. We have momentum at the right time of the season and are still looking fresh, so we have put ourselves in a really strong position."
Brighton have now gone seven games without defeat in the Championship and Poyet believes his squad's strength in depth has been the catalyst for such a strong finish to the season.
He added: "I had the best bench I have ever had as a manager.
"When you have the power, quality and experience we had on the bench, win 6-1, and still don't use players like Leonardo Ulloa and Vicente Rodriguez, you know it's a good day. It was an excellent display. People at home who couldn't get a ticket would have regretted the situation."