The experienced left-back begins a three-match ban after he was sent off late on in the 2-1 defeat at Hull on Tuesday night.
It is a problem Rams boss Nigel Clough could do without, with fellow defenders Mark O'Brien, James O'Connor and captain Shaun Barker already absent due to knee injuries.
Centre-half Jake Buxton will be assessed ahead of the weekend after recently overcoming a medial knee ligament injury.
With O'Brien and O'Connor sidelined, Clough may continue with right-back John Brayford as a central defender, leaving Kieron Freeman, Valentin Gjokaj and Michael Hoganson all pushing for places in the back four.
Teenage striker Mason Bennett will be available for selection after returning from international duty in the Algarve with England Under-17s.