Owen, who has scored once in a Potters career that to date has amounted to only six substitute appearances and one start, announced last week that he is to retire from playing at the end of the season.
Since joining at the start of the campaign, the 33-year-old striker - previously a free agent following his release by Manchester United - has yet again spent plenty of time recovering from injuries, while on several occasions when he has been deemed fit enough to be selected for the match-day squad, he has subsequently been left on the bench.
Nonetheless, Pulis claims Owen has been a "great signing" for Stoke.
Asked if he had any sense of regret over recruiting the former England international, Pulis said: "Not at all. He has been fantastic around the place.
"He has been a great signing - if you look at it financially, it has been a great deal for the football club in lots of respects.
"Michael was really unlucky at the beginning of the season, picking up those couple of injuries.
"If he had got through that and pushed on, then we might be talking about different things now. But it is what has happened to Michael over the past few years."
When it was suggested to him that Owen could still play an important role for goal-shy Stoke this term, Pulis added: "We are desperate for him to be involved and be a part of it, and hopefully he can do that."